I dislike MS Office, both because of the price and the bloated feature set, and have tried and hated most of the alternatives, including OpenOffice, Google Docs and Spreadsheets, and Zoho. OpenOffice is free, but poorly constructed, and thus solves the wrong half of the problem. Google D&S (and all the other online html-based office suites) make efficient working impossible and simply don’t export well.
That leaves iWork, which I can no longer ignore because Apple just added a spreadsheet app. The price is right at 5 licenses for $99, and if this new “Numbers” is anything near what Scoble is hyping it up to be I think I may finally settle on a productivity suite.